| 货号 | 0348/50 |
| 别名 | 2-(2-Benzofuranyl)-2-imidazoline hydrochloride |
| 供应商 | Tocris |
| 生物活性 | High affinity I2 ligand (Ki = 9.8 nM). Putative I2 agonist; potentiates morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 222.67 |
| 分子式 | C11H10N2O.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 89196-95-2 |
| 参考文献 | MacInnes and Duty (2004) Locomotor effects of imidazoline I2-site-specific ligands and monoamine oxidase inhibitors in rats with a unilateral 6-hydroxydopamine lesion of the nigrostriatal pathway. Br.J.Pharmacol. 143 952. PMID: 15545290. Sanchez-Blasquezet al (2000) Activation of I2-imidazoline receptors enhances supraspinal morphine analgesia in mice: a model to detect agonist and antagonist activities at these receptors. Br.J.Pharmacol. 130 146. PMID: 10781010. Alemanyet al (1997) Labelling of I2B-imidazoline receptors by [3H]2-(2-benzofuranyl)-2-imidazoline (2-BFI) in rat brain and liver: characterization, regulation and relation to monoamine oxidase enzymes. Naunyn Schmiedebergs Arch.Pharmacol. 356 39. PMID: 9228188. |