Oligomycin D
货号：
20184-2.5mg 基本售价：
8666.0 元 规格：
2.5 mg
产品信息
概述| 货号 | 20184-2.5mg |
| 描述 | Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport.1 Oligomycin D is reported to inhibit K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cytotoxic to SW620 colon cancer cells with an IC50 value of 36 µM.2 |
| 别名 | 26-Demethyloligomycin A;RR 32705;Rutamycin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Inoue, S.,Mizutani, A.,Sugita, R., et al. Purification and characterization of a novel protein activator of Ca2+/calmodulin-dependent protein kinase I. Biochemical and Biophysical Research Communications 215(3), 861-867 (1995).
2.Salim, A.A.,Tan, L.,Huang, X.-C., et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Organic & Biomolecular Chemistry 14(2), 711-715 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 777 |
| 分子式 | C44H72O11 |
| CAS号 | 1404-59-7 |
| 稳定性 | ≥ 2 years |
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