| 货号 | 20291-10mg |
| 描述 | α-Muricholic acid is a primary bile acid in rodents.1,2 Muricholic acids regulate bile acid synthesis in mice via a positive feedback mechanism.3 Elevated levels of muricholic bile acids correlate with resistance to dietary-induced steatosis and weight gain.4 |
| 别名 | 5β-Cholanic Acid-3α,6β,7α-triol;α-MCA; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Eyssen, H.J.,Parmentier, G.G. and Mertens, J.A. Sulfate bile acids in germ-free and conventional mice. European Journal of Biochemistry 66(3), 507-514 (1976). 2.Uehara, T.,Xi Peng, X.,Bennett, B., et al. c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation. Transplantation 78(3), 324-332 (2004). 3.Hu, X.,Bonde, Y.,Eggertsen, G., et al. Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism. J. Intern. Med. 275(1), 27-38 (2014). 4.Bonde, Y.,Eggertsen, G. and Rudling, M. Mice abundant in muricholic bile acids show resistance to dietary induced steatosis, weight gain, and to impaired glucose metabolism. PLoS One 11(1), e0147772 (2016). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 408.6 |
| 分子式 | C24H40O5 |
| CAS号 | 2393-58-0 |
| 稳定性 | ≥ 2 years |
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