| 货号 | 1801/50 |
| 别名 | 8,9-Dichloro-2,3,4,4a-tetrahydro-1H |
| 供应商 | Tocris |
| 生物活性 | Potent and selective 5-HT2C receptor agonist (Ki = 4 nM; EC50 = 12 nM). Antidepressant following systemic administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 308.59 |
| 分子式 | C11H11Cl2N3O.HCl |
| CAS号 | 75704-24-4 |
| 参考文献 | Jensenet al (2013) Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive properties. J.Med.Chem. 56 1211. PMID: 23301527. Cryan and Lucki (2000) Antidepressant-like behavioral effects mediated by 5-hydroxytryptamine2C receptors. J.Pharmacol.Exp.Ther. 295 1120. PMID: 11082448. Welmakeret al (2000) Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines. Bioorg.Med.Chem.Lett. 10 1991. PMID: 10987434. |