| 货号 | 2735/50 |
| 别名 | 1-[2-(3,4-Dihydro-1H-2-benzopyran-1 |
| 供应商 | Tocris |
| 生物活性 | Antipsychotic agent. Displays high affinity for dopamine D4 and serotonergic 5-HT2A receptors and relatively weak affinity at D2 receptors (Ki values are 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D4, 5-HT2A, 5-HT1A,α1, D2, D3, D1,α2 and muscarinic receptors respectively). Inhibits exploratory locomotor activity and antagonizes d-amphetamine-induced locomotor stimulation in rats. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 413.36 |
| 分子式 | C21H25FN2O.2HCl |
| 可溶性/溶解性 | Soluble to 10 mM in water |
| CAS号 | 170856-41-4 |
| 参考文献 | Goudieet al (1998) Discriminative stimulus properties of the atypical neuroleptic clozapine in rats: tests with subtype selective receptor ligands. Behav.Pharmacol. 9 699. PMID: 9890260. Tanget al (1997) PNU-96415E, a potential antipsychotic agent with clozapine-like pharmacological properties. J.Pharmacol.Exp.Ther. 281 440. PMID: 9103528. |