| 货号 | 1380/50 |
| 别名 | 2-(Phosphonomethyl)pentane-1,5-dioi |
| 供应商 | Tocris |
| 生物活性 | Highly potent and selective inhibitor of |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 226.12 |
| 分子式 | C6H11O7P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 173039-10-6 |
| 参考文献 | Rahnet al (2012) Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis. Proc.Natl.Acad.Sci.U S A (Epub ahead of print]. PMID: 23169655. Thomaset al (2003) NAALADase inhibition protects motor neurons against chronic glutamate toxicity. Eur.J.Pharmacol. 471 177. PMID: 12826236. Slusheret al (1999) Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury. Nat.Med. 5 1396. PMID: 10581082. Jacksonet al (1996) Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase. J.Med.Chem. 39 619. PMID: 8558536. |