| 货号 | 2492/50 |
| 别名 | 4-Methyl-3-[(1-methyl-4-nitro-1H-im |
| 供应商 | Tocris |
| 生物活性 | Novel, non-toxic immunosuppressive agent. Inhibits human mixed lymphocyte reaction in vitro(ED50 = 2.7 μM) and prolongs skin graft survival in mice. Produces a 98.1% reduction in antibody response following oral administration in rabbits. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 240.24 |
| 分子式 | C7H8N6O2S |
| 可溶性/溶解性 | Soluble to 10 mM in water |
| CAS号 | 177653-76-8 |
| 参考文献 | Al-Safiet al (2003) Comparison of the effects of azathioprine and its novel non-mercaptopurine analog on antibody response in rabbits. Pol.J.Pharmacol. 55 239. PMID: 12926553. Crawfordet al (1996) Rational design of novel immunosuppressive drugs: analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects. J.Med.Chem. 39 2690. PMID: 8709098. |