| 货号 | 1131/50 |
| 别名 | 2-(2-Ethyl-2,3-dihydro-2-benzofuran |
| 供应商 | Tocris |
| 生物活性 | Antagonist of the atypical imidazoline binding site (putative I3 receptor) of pancreatic β-cells. Selectively blocks efaroxan-induced insulin secretion in vitroandin vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 214.27 |
| 分子式 | C13H14N2O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 189224-48-4 |
| 参考文献 | Mayer and Taberner (2002) Effects of the imidazoline ligands efaroxan and KU14R on blood glucose in the mouse. Eur.J.Pharmacol. 454 95. PMID: 12409010. Chanet al (1997) The putative endogenous imidazoline receptor ligand, clonidine-displacing substance, is a potent insulin secretagogue in rat and human islets of Langerhans. Br.J.Pharmacol. 120 926. PMID: 9138700. Chanet al (1997) Clotrimazole and efaroxan stimulate insulin secretion by different mechanisms in rat pancreatic islets. Naunyn Schmiedebergs Arch.Pharmacol. 356 763. PMID: 9453462. |