Ethyl-L-NIO (hydrochloride)
货号：
10012088-100mg 基本售价：
8428.0 元 规格：
100 mg
产品信息
概述| 货号 | 10012088-100mg |
| 描述 | Ethyl-L-NIO, the saturated analog of vinyl-L-NIO, is a modestly selective NOS inhibitor. The Ki values for inhibition of nNOS, eNOS, and iNOS by ethyl-L-NIO are 5.3, 18, and 12 µM, respectively, as determined using initial rate measurements.1 However when evaluating the Ki/Km ratio, ethyl-L-NIO does not show biologically significant selectivity for nNOS over eNOS, and instead favors iNOS (Ki/Km = 3.79, 5, and 0.96 µM, respectively).1 Although ethyl-L-NIO inhibits nNOS, it does not inactivate nNOS in the presence of NADPH and O2.1 |
| 别名 | L-N5-(1-Iminobutyl)ornithine hydrochloride; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Babu, B.R. and Griffith, O.W. N5-(1-Imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase. The Journal of Biological Chemisty 273, 8882-8889 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 237.7 |
| 分子式 | C9H19N3O2 • HCl |
| CAS号 | 150403-97-7 |
| 稳定性 | ≥ 1 year |
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