1-Stearoyl-2-Arachidonoyl PC-d8
货号：
10009431-1mg 基本售价：
8428.0 元 规格：
1 mg
产品信息
概述| 货号 | 10009431-1mg |
| 描述 | 1-Stearoyl-2-Arachidonoyl PC-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of SAPC by GC- or LC-mass spectrometry. Oxidation of phospholipids in low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.11-stearoyl-2-arachidonoyl-sn-Glycero-3-phosphocholine (SAPC) is one of the major phospholipid species in LDL. Upon oxidation, SAPC that been shown to induce monocyte-endothelial interactions.2 |
| 别名 | SAPC-d8;1-Stearoyl-2-Arachidonoyl Phosphatidylcholine-d8; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Milne, G.L.,Seal, J.R.,Havrilla, C.M., et al. Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. Journal of Lipid Research 46, 307-319 (2005).
2.Subbanagounder, G.,Leitinger, N.,Schwenke, D.C., et al. Determinants of bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position. Arteriosclerosis, Thrombosis, and Vascular Biology 20, 2248-2254 (2000).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d8) |
| 计算分子量 | 818.2 |
| 分子式 | C46H76D8NO8P |
| CAS号 | 161922-50-5 |
| 稳定性 | ≥ 1 year |
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