| 货号 | 13522-250mg |
| 描述 | Trandolapril is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.93 nM).1 Formulations containing trandolapril, with or without the calcium channel blocker verapamil (Item No. 14288), are effective against certain cardiovascular disorders, including essential hypertension.2,3 ACE inhibitors, including trandolapril, also have neuroprotective effects in animal models.4 |
| 别名 | RU-44570; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Leung, D.,Abbenante, G. and Fairlie, D.P. Protease inhibitors: Current status and future prospects. J. Med. Chem. 43(3), 305-341 (2000). 2.Diaz, A. and Ducharme, A. Update on the use of trandolapril in the management of cardiovascular disorders. Vasc. Health Risk Manag. 4(6), 1147-1158 (2008). 3.Reynolds, N.A.,Wagstaff, A.J. and Keam, S.J. Trandolapril/verapamil sustained release: A review of its use in the treatment of essential hypertension. Drugs 65(13), 1893-1914 (2005). 4.Kaur, P.,Muthuraman, A. and Kaur, M. The implications of angiotensin-converting enzymes and their modulators in neurodegenerative disorders: current and future perspectives. ACS Chem Biol. 6(4), 508-521 (2015). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 430.5 |
| 分子式 | C24H34N2O5 |
| CAS号 | 87679-37-6 |
| 稳定性 | ≥ 2 years |
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