PKCα (C2-4) Inhibitor Peptide
货号：
17478-5mg 基本售价：
8190.0 元 规格：
5 mg
产品信息
概述| 货号 | 17478-5mg |
| 描述 | The C2 domain of conventional PKC isoforms mediates calcium-dependent translocation. Peptides from that region can block PKC translocation and inhibit function, both in cells and cell lysates.1 PKCα (C2-4) inhibitor peptide is a synthetic peptide that blocks PKC activity in HepG2 cells stimulated with calcium and pancreastatin when applied at 10 µM.2 |
| 别名 | Protein Kinase Cα (C2-4) Inhibitor Peptide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ron, D.,Luo, J., and Mochly-Rosen, D. C2 region-derived peptides inhibit translocation and function of β protein kinase C in vivo. The Journal of Biological Chemisty 270(41), 24180-24187 (1995).
2.Gayen, J.R.,Saberi, M.,Schenk, S., et al. A novel pathway of insulin sensitivity in chromogranin A null mice: A crucial role for pancreastatin in glucose homeostasis. The Journal of Biological Chemisty 248(42), 28498-28509 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1107.2 |
| 分子式 | C47H74N14O17 |
| 稳定性 | ≥ 2 years |
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