Apixaban
货号：
15427-50mg 基本售价：
8190.0 元 规格：
50 mg
产品信息
概述| 货号 | 15427-50mg |
| 描述 | Factor Xa is an integral enzyme of the coagulation cascade that catalyzes the formation of thrombin. Apixaban is an orally available, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM).1 Apixaban is an effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.1,2 |
| 别名 | BMS 562247-01;Eliquis; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Turpie, A.G.G. Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseases. Arterioscler. Thromb. Vasc. Biol. 27(6), 1238-1247 (2007).
2.Committee, A.S.,Investigators,Alexander, J.H., et al. Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: Results of the apixaban for prevention of acute ischemic and safety events (APPRAISE) trial. Circulation 119(22), 2877-2885 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 459.5 |
| 分子式 | C25H25N5O4 |
| CAS号 | 503612-47-3 |
| 稳定性 | ≥ 2 years |
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