Toxin B from Clostridium difficile
货号：
19665-50ug 基本售价：
8050.0 元 规格：
50 ug
产品信息
概述| 货号 | 19665-50ug |
| 描述 | Toxin B from Clostridium difficile, also known as TcdB, is a cytotoxin that has glucosyltransferase and cysteine protease activities. It inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion.1,2 Toxin B can induce activation of the inflammasome and apoptosis.3 While both toxin A (Item No. 19664) and toxin B inactivate Rho family GTPases, toxin B more potently induces mammalian cell rounding in culture.2 |
| 别名 | TcdB; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chen, S.,Sun, C.,Wang, H., et al. The role of rho GTPases in toxicity of Clostridium difficile toxins. Toxins (Basel) 7(12), 5254-5267 (2016).
2.Pruitt, R.N., and Lacy, D.B. Toward a structural understanding of Clostridium difficile toxins A and B. Front.Cell.Infect.Microbiol. 2(28), (2012).
3.Di Bella, S.,Ascenzi, P.,Siarakas, S., et al. Clostridium difficile toxins A and B: Insights into pathogenic properties and extraintestinal effects. Toxins (Basel) 8(5), (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | 2-8 |
| 纯度 | ≥90% (estimated by SDS-PAGE) |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
