货号 | 2897/50 |
别名 | 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide |
供应商 | Tocris |
生物活性 | Non-competitive inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity. Does not inhibit other small GTPases. Blocks endocytic pathways dependent on dynamin and inhibits cell spreading and migration of BSC1 cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >99 % |
计算分子量 | 322.32 |
分子式 | C18H14N2O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 5 mM in ethanol |
CAS号 | 304448-55-3 |
参考文献 | Maciaet al (2006) Dynasore, a cell-permeable inhibitor of Dynamin. Develop.Cell 10839. Newtonet al (2006) Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis. Proc.Natl.Acad.Sci.USA 10317955. Thompson and McNiven (2006) Discovery of a new 'dynasore'. Nat.Chem.Biol. 2 355. PMID: 16783339. |