SI-2
货号：
19565-25mg 基本售价：
7966.0 元 规格：
25 mg
产品信息
概述| 货号 | 19565-25mg |
| 描述 | SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3). It has been shown to selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells through direct physical interactions with SRC-3.1 SI-2 induces death in various breast cancer cells with IC50 values of 3-20 nM without affecting normal cell viability.1 At 2 mg/kg, SI-2 can also inhibit primary tumor growth and reduce SRC-3 protein levels in an MDA-MB-468 breast cancer mouse model.1 |
| 别名 | EPH 116; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Song, X.,Chen, J.,Zhao, M., et al. Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3. Proceedings of the National Academy of Sciences of the United States of America 113(18), 4970-4975 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 265.3 |
| 分子式 | C15H15N5 |
| CAS号 | 380537-35-9 |
| 稳定性 | ≥ 2 years |
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