货号 | 2466/50 |
别名 | 5-Bromo-6-(2-imidazolin-2-ylamino)q |
供应商 | Tocris |
生物活性 | Water-soluble form of UK 14,304 (Cat. No. 0425). Full α2 adrenergic agonist. Centrally active following systemic administration in vivo. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 442.23 |
分子式 | C11H10BrN5.C4H6O6 |
可溶性/溶解性 | Soluble to 50 mM in water |
CAS号 | 59803-99-5 |
参考文献 | Chopinet al (1999) Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther. 288 798. PMID: 9918591. Macdonaldet al (1997) Gene targeting - homing in on α2-adrenoceptor-subtype function. TiPS 18 211. PMID: 9227000. Andornet al (1988) Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity states with α2-adrenergic selectivity and different affinities for GTP. Life Sci. 43 1805. PMID: 2904634. Cambridge (1981) UK-14,304, a potent and selective alpha2-gonist for the characterisation of alpha-adrenoceptor subtypes. Eur.J.Pharmacol. 72 413. PMID: 6115759. |