TMCB (50 MG)
货号：
3675/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 3675/50 |
| 别名 | 2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid |
性能| 供应商 | Tocris |
| 生物活性 | Dual-kinase inhibitor; inhibits both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50 μM for both CK2 and ERK8). Displays selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki values are 0.25, 8.65, 11.90 and 15.25 μM for CK2, PIM1, DYRK1a and HIPK2 respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 534.82 |
| 分子式 | C11H9Br4N3 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| 参考文献 | Paganoet al (2008) The selectivity of inhibitors of protein kinase CK2: an update. Biochem.J. 415 353. PMID: 18588507. |
