货号 | 0631/50 |
别名 | 8-[(2,3-Dihydro-1,4-benzodioxin-2-y |
供应商 | Tocris |
生物活性 | 5-HT1A antagonist. More active and selective than spiperone. Also a very potent α2C adrenergic receptor antagonist. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 379.46 |
分子式 | C22H25N3O3 |
可溶性/溶解性 | Soluble to 10 mM in DMSO |
CAS号 | 1054-88-2 |
参考文献 | Bylundet al (1992) Pharmacological characteristics of α2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning. Mol.Pharmacol. 42 1. PMID: 1353247. Schoeffter and Hoyer (1988) Centrally acting hypotensive agents with affinity for 5-HT1A binding sites inhibit forskolin-stimulated adenylate cyclase activity in calf hippocampus. Br.J.Pharmacol. 95 975. PMID: 3207999. Nelson and Taylor (1986) Spiroxatrine: a selective serotonin 1A receptor antagonist. Eur.J.Pharmacol. 124 207. PMID: 3720840. |