| 货号 | 1215/50 |
| 别名 | 6-Methyl-2-(phenylazo)-3-pyridinol |
| 供应商 | Tocris |
| 生物活性 | A highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype; displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 213.24 |
| 分子式 | C12H11N3O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 31993-01-8 |
| 参考文献 | Varneyet al (1999) SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5. J.Pharmacol.Exp.Ther. 290 170. PMID: 10381773. Varneyet al (1999) Characterisation of SIB-1757 and SIB-1893: highly selective antagonists at metabotropic glutamate receptor subtype 5. Br.J.Pharmacol. 126248P. |