Sephin 1 (50 MG)
货号：
5553/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5553/50 |
| 别名 | (2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1. Does not bind PPP1R15B or have α2 adrenergic agonist activity. Cytoprotective in endoplasmic reticulum stressed cells in vitro. Prevents defects associated with protein misfolding in a mouse Charcot-Marie Tooth-1B model. Orally available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 258.66 |
| 分子式 | C8H9ClN4.CH2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Daset al (2015) Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science 348 239. PMID: 25859045. |
