| 货号 | 0990/50 |
| 别名 | 1-(4-Amino-5-chloro-2-methoxyphenyl |
| 供应商 | Tocris |
| 生物活性 | A potent and selective 5-HT4 partial agonist, with a pKi of 8.8 at 5-HT4 sites in guinea pig striatum, but < 6.0 at several other receptors including 5-HT1A, 1D, 2A, 2C, D1, D2 and M1-3. It is active in vivo and has an intrinsic activity compared to 5-HT of 0.6. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 454.41 |
| 分子式 | C18H28ClN3O4S.HCl |
| 可溶性/溶解性 | Soluble to 80 mM in water |
| CAS号 | 168986-61-6 |
| 参考文献 | Fontanaet al (1997) The effects of novel, selective 5-hydroxytryptamine (5HT)4 ligands in rat spatial navigation. Neuropharmacology 36 689. PMID: 9225295. Eglenet al (1995) Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitroandin vivo. Br.J.Pharmacol. 115 1387. PMID: 8564196. Eglenet al (1995) Central 5-HT4 receptors. TiPS 16 391. PMID: 8578609. |