| 货号 | 1031/50 |
| 别名 | 2-[4-(1,3-Benzodioxol-5-ylmethyl)-1 |
| 供应商 | Tocris |
| 生物活性 | A direct dopamine agonist, in clinical use for treatment of dopaminergic system dysfunction. Recent work suggests that it is selective for the D3 subtype, for which it has 20 times higher affinity than for D2, and possesses no significant affinity for D1receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 371.27 |
| 分子式 | C16H18N4O2.2HCl |
| 可溶性/溶解性 | Soluble to 25 mM in water |
| CAS号 | 78213-63-5 |
| 参考文献 | Cagnottoet al (1996) In vitro affinity of piribedil for dopamine D3 receptor subtypes, an autoradiographic study. Eur.J.Pharmacol. 313 63. PMID: 8905329. Jenne (1992) Parkinson's disease: pathological mechanisms and actions of piribedil. J.Neurol. 239 S2. PMID: 1634907. Offermeier and van Rooyen (1986) A comparative study of the locomotor activity effects of apomorphine and the 'atypical dopamine agonists' (piribedil and S36080). Life Sci. 38 895. PMID: 3081774. Merck Index 127648. |