| 货号 | 3645/50 |
| 别名 | 4-[[(1,1-Dimethylethyl)oxoimino]met |
| 供应商 | Tocris |
| 生物活性 | Free radical trapping agent. Reduces infarct size and preserves brain function in several animal models of acute ischemic stroke. Neuroprotectant. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 381.33 |
| 分子式 | C11H13NNa2O7S2 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 168021-79-2 |
| 参考文献 | Culotet al (2009) Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. Brain Res. 1294 144. PMID: 19631615. Sydserffet al (2002) Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window. Br.J.Pharmacol. 135 103. PMID: 11786485. Peelinget al (2001) Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059), a free radical trapping agent, in a rat model of hemorrhagic stroke. Neuropharmacology 40 433. PMID: 11166336. |