| 货号 | 0573/50 |
| 别名 | N-Methyl-1H-imidazole-4-ethanamine dihydrochloride |
| 供应商 | Tocris |
| 生物活性 | Potent histamine agonist, particularly at H3 receptors (potency relative to histamine is 81, 185, and 270% at H1, H2 and H3 respectively). Also displays agonist properties at H4 receptors to which it binds with moderate affinity (Ki = 23 nM). |
| 运输条件 | Ambient |
| 存放说明 | Ambient |
| 计算分子量 | 198.09 |
| 分子式 | C6H11N3.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 673-50-7 |
| 参考文献 | Zweiget al (1992) Characterization of digitonin-solubilized bovine brain H3 histamine receptor coupled to a guanine nucleotide-binding protein. J.Neurochem. 59 1661. PMID: 1328529. Hillet al (1990) Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45. PMID: 2164693. Schwartzet al (1990) A third histamine receptor subtype - characterization, localization and functions of the H3-receptor. Agents Actions 30 13. PMID: 1695431. |