NK 252 (50 MG)
货号：
5293/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5293/50 |
| 别名 | N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea |
性能| 供应商 | Tocris |
| 生物活性 | Nrf2 activator; interacts with the Nrf2-binding site of Keap1. Downregulates the expression of fibrogenic genes and increases antioxidant effects in NASH rat models of liver disease. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 285.26 |
| 分子式 | C13H11N5O3 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| 参考文献 | Shimozonoet al (2013) Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol.Pharmacol. 84 62. PMID: 23592516. |
