| 货号 | 2844/50 |
| 别名 | 4-Amino-5-chloro-2-ethoxy-N-[[4-[(4 |
| 供应商 | Tocris |
| 生物活性 | 5-HT4 receptor agonist and 5-HT3 receptor antagonist. Displays no activity at D2,α1,α2, 5-HT1 and 5-HT2 receptors. Gastroprokinetic agent; increases gastric emptying in rats and stimulates gastric motor actvity in conscious dogs. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 614.02 |
| 分子式 | C21H25ClFN3O3.C6H8O7 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 112885-42-4 |
| 参考文献 | Mineet al (1997) Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivoandin vitro. J.Pharmacol.Exp.Ther. 283 1000. PMID: 9399969. Yoshidaet al (1993) Pharmacological effects of the new gastroprokinetic agent mosapride citrate and its metabolites in experimental animals. Arzneim.-Forsch. 431078. Yoshidaet al (1989) AS-4370, a novel gastrokinetic agent free of dopamine D2 receptor antagonist properties. Arch.Int.Pharmacodyn.Ther. 300 51. PMID: 2533479. |