MN 64 (50 MG)
货号：
5084/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5084/50 |
| 别名 | 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective tankyrase (TNKS) inhibitor (IC50 values are 6 and 72 nM for TNKS1 and TNKS2 respectively). Has no significant effect on PARP-1 or PARP-2 (IC50>19μM). Inhibits WNT/β-catenin signaling-dependent Super-TopFlash (STF) luciferase activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 264.32 |
| 分子式 | C18H16O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Narwalet al (2013) Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem. 56 7880. PMID: 24116873. |
