ML 382 ( )
货号：
5738/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5738/50 |
| 别名 | 2-[(Cyclopropylsulfonyl)amino]-N-(2-ethoxyphenyl)benzamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective MrgX1 (SNSR4) positive allosteric modulator (EC50 = 190 nM). Exhibits selectivity for MrgX1 over MrgX2, MrgC11 and a panel of 68 other GPCRs, ion channels and transporters. Enhances BAM (8-22) potency at MrgX1 by 7-fold. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 360.43 |
| 分子式 | C18H20N2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol with gentle warming |
| 参考文献 | Wenet al (2015) Discovery and characterization of 2-(cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide, ML382: a potent and selective positive allosteric modulator of MrgX1. ChemMedChem 10 57. PMID: 25209672. |
