| 货号 | 0941/50 |
| 别名 | 6-Chloro-2-(1-piperazinyl)pyrazine hydrochloride |
| 供应商 | Tocris |
| 生物活性 | 5-HT receptor agonist; displays selectivity for 5-HT2C over 5-HT2A(IC50 values are 0.028 and 0.42 μM for human 5-HT2C and 5-HT2A receptors expressed in HEK293 cells respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 235.12 |
| 分子式 | C8H11CIN4.HCl |
| 可溶性/溶解性 | Soluble to 50 mM in water with gentle warming |
| CAS号 | 64022-27-1 |
| 参考文献 | Jensenet al (2013) Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-dazepin-3-ol analogues: novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive properties. J.Med.Chem. 56 1211. PMID: 23301527. Hemrick-Luecke and Fuller (1996) Involvement of 5-HT2A receptors in the elevation of rat serum corticosterone concentration by quipazine and MK-212. Eur.J.Pharmacol. 311 207. PMID: 8891601. Conn and Sanders-Bush (1987) Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT2 and 5-HT1C) receptors. J.Pharmacol.Exp.Ther. 242 552. PMID: 3039120. |