LOC14 (50 MG)
货号：
5606/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5606/50 |
| 别名 | 2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one |
性能| 供应商 | Tocris |
| 生物活性 | High affinity protein disulfide isomerase (PDI) modulator (Kd = 62 nM). Forces PDI to adopt an oxidized conformation and suppresses its activity. Neuroprotective. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 317.41 |
| 分子式 | C16H19N3O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Kaplanet al (2015) Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective. Proc.Natl.Acad.Sci.U.S.A. 112 E2245. PMID: 25848045. |
