| 货号 | 5082/50 |
| 别名 | 3-[[(2-Methylphenyl)methyl]thio]-6- |
| 供应商 | Tocris |
| 生物活性 | Increases expression of glutamate transporter EAAT2 in PA-EAAT2 cells. Displays neuroprotective activity in vivo. Shown to improve learning and memory, restore synaptic integrity and reduce amyloid plaque burden in APPSw/Ind mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 293.39 |
| 分子式 | C17H15N3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Linet al (2013) : Mechanism of LDN-212320 induction of glutamate transporter EAAT2 expression . Society for Neuroscience (Abstract) 99. Takahashiet al (2013) A small molecule modulator of glutamate transporter EAAT2 ameliorates Alzheimer |