| 货号 | 1588/50 |
| 别名 | (1R,3S)-rel-3-(3,4-Dichlorophenyl)- |
| 供应商 | Tocris |
| 生物活性 | Potent monoamine uptake inhibitor. Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (Ki values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo. |
| 运输条件 | Ambient |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 328.67 |
| 分子式 | C16H15Cl2N.HCl |
| 可溶性/溶解性 | Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO |
| CAS号 | 86939-10-8 |
| 参考文献 | Guet al (2000) Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline. J.Med.Chem. 43 4868. PMID: 11123996. Neguset al (1999) Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys. J.Pharmacol.Exp.Ther. 291 60. PMID: 10490887. Hyttel and Larsen (1985) Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of dopamine, noradrenaline and serotonin. J.Neurochem. 44 1615. PMID: 2580950. |