INCA-6 (50 MG)
货号：
2162/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 2162/50 |
| 别名 | 9,10-Dihydro-9,10[1',2']-benzenoanthracene-1,4-dione |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (Kd = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 284.31 |
| 分子式 | C20H12O2 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| CAS号 | 3519-82-2 |
| 参考文献 | Roehrlet al (2004) Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules. Proc.Natl.Acad.Sci.USA 1017554. |
