EXP 3174 (50 MG)
货号：
5728/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5728/50 |
| 别名 | 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective noncompetitive AT1 receptor antagonist (IC50 = 37 nM). Reduces blood pressure in a rat model. Active metabolite of losartan potassium (Cat.No. 3798). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 436.89 |
| 分子式 | C22H21ClN6O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Wonget al (1990) Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent. J.Pharmacol.Exp.Ther. 255 211. PMID: 2213556. |
