货号 | 4056/50 |
别名 | [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα, |
供应商 | Tocris |
生物活性 | Binds and stabilizes microtubules; leads to cell cycle arrest and apoptosis. Displays significant antitumor activity in ovarian and gastric tumors. Prevents microtubule depolymerization and disassembly in the absence of GTP. Exhibits cytotoxic activity. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 807.88 |
分子式 | C43H53NO14 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
CAS号 | 114977-28-5 |
参考文献 | Ramaswamy and Puhalla (2006) Docetaxel: a tubulin-stabilizing agent approved for the management of several solid tumors. Drugs Today (Barc) 42 265. PMID: 16703123. Lyseng-Williamson and Fenton (2005) Docetaxel: a review of its use in metastatic breast cancer. Drugs 65 2513. PMID: 16296875. |