Napabucasin (50 MG)
货号：
5522/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5522/50 |
| 别名 | 2-Acetylnaphtho[2,3-b]furan-4,9-dione |
性能| 供应商 | Tocris |
| 生物活性 | STAT3 inhibitor. Blocks spherogenesis of cancer stem cells (CSC), but not hematopoietic stem cells. Inhibits PaCa-2 xenograft tumor growth in mice, even after cessation of treatment, and decreases population of CSCs in PaCa-2 tumors from treated mice. Also blocks spleen and liver metastases of colon cancer cells in a mouse model. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 240.21 |
| 分子式 | C14H8O4 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Liet al (2015) Suppression of cancer relapse and metastasis by inhibiting cancer stemness. Proc.Natl.Acad.Sci.USA. 112 1839. PMID: 25605917. |
