| 货号 | 2436/50 |
| 别名 | 4'-Octyl-[1,1'-biphenyl]-4-carboxylic |
| 供应商 | Tocris |
| 生物活性 | Potent, isoform-selective RARβ2 receptor agonist (pEC50 values are 6.9, 5.7 and 5.6 at RARβ2, RARβ1 and RARα respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 310.44 |
| 分子式 | C21H26O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| CAS号 | 59662-49-6 |
| 参考文献 | Lundet al (2009) Design, synthesis, and structure-activity analysis of isoform selective retinoic acid receptor ligands. J.Med.Chem. 52 1540. PMID: 19239230. Lundet al (2005) Discovery of a potent, orally available, and isoform-selective retinoic acid β2 receptor agonist. J.Med.Chem. 48 7517. PMID: 16302793. |