货号 | 0620/50 |
别名 | 4-Phenyl-1-(4-phenylbutyl)piperidin |
供应商 | Tocris |
生物活性 | σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 409.52 |
分子式 | C21H27N.C4H4O4 |
可溶性/溶解性 | Soluble to 25 mM in ethanol and to 25 mM in DMSO |
参考文献 | Whittemoreet al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326. PMID: 9223571. Glennonet al (1991) Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 34 3360. PMID: 1662725. |