| 货号 | 1415/50 |
| 别名 | N-[[3-(Aminomethyl)phenyl]methyl]-e |
| 供应商 | Tocris |
| 生物活性 | Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM). Selective over nNOS and eNOS (Ki values are 2 and 50 μM respectively). Cell-permeable and active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 250.17 |
| 分子式 | C10H15N3.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 180001-34-7 |
| 参考文献 | Parmentieret al (1999) Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain injury. Br.J.Pharmacol. 127 546. PMID: 10385257. Garveyet al (1997) 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitroandin vivo. J.Biol.Chem. 272 4959. PMID: 9030556. Thomsenet al (1997) Selective inhibition of inducible nitric oxide inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor. Cancer Res. 57 3300. PMID: 9242464. |