货号 | 18196-5mg |
描述 | Equisetin is a fungal metabolite isolated from Fusarium that demonstrates antibiotic and cytotoxic activity.1,2 It inhibits HIV-1 integrase with an IC50 value of 7-20 µM.3 Equisetin is also reported to block the mitochondrial transport of ATP, inorganic phosphate, and succinate via a currently undetermined mechanism.4 |
供应商 | Cayman |
应用文献 | |
1.Desjardins, A.E. and Proctor, R.H. Molecular biology of Fusarium mycotoxins. Int.J.Food Microbiol. 119, 47-50 (2007). 2.Patham, B.,Duffy, J.,Lane, A., et al. Post-translational import of protein into the endoplasmic reticulum of a trypanosome: An in vitro system for discovery of anti-trypanosomal chemical entities. Biochemistry Journal 419(2), 507-517 (2009). 3.Singh, S.B.,Zink, D.L.,Goetz, M.A., et al. Equisetin and a novel opposite stereochemical homolog phomasetin, two fungal metabolites as inhibitors of HIV-1 integrase. Tetrahedron Letters 39, 2243-2246 (1998). 4.König, T.,Kapus, A. and Sarkadi, B. Effects of equisetin on rat liver mitochondria: Evidence for inhibition of substrate anion carriers of the inner membrane. Journal of Bioenergetics and Biomembranes 25(5), 537-545 (1993). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥99% |
计算分子量 | 373.5 |
分子式 | C22H31NO4 |
CAS号 | 57749-43-6 |
稳定性 | ≥ 2 years |
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