KDdiA-PC
货号：
62935-10mg 基本售价：
7840.0 元 规格：
10 mg
产品信息
概述| 货号 | 62935-10mg |
| 描述 | Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.1 Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position.2 KDdiA-PC is one of the most potent CD36 ligands among the oxLDL species.3 KDdiA-PC confers CD-36 scavenger receptor binding affinity to LDL at a frequency of only two to three KDdiA-PC molecules/LDL particle, and may be one of the more important structural determinants of oxLDL. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Podrez, E.A.,Febbraio, M.,Sheibani, N., et al. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. Journal of Clinical Investigation 105(8), 1095-1108 (2000).
2.Podrez, E.A.,Batyreva, E.,Shen, Z., et al. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. The Journal of Biological Chemisty 277 (41), 38517-38523 (2002).
3.Podrez, E.A.,Batyreva, B.,Shen, Z., et al. Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. The Journal of Biological Chemisty 277(41), 38503-38516 (2002).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥98% |
| 计算分子量 | 719.9 |
| 分子式 | C36H66NO11P |
| CAS号 | 439904-34-4 |
| 稳定性 | ≥ 1 year |
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