5-trans Fluprostenol
货号:
16776-10mg 基本售价:
7840.0 元 规格:
10 mg
产品信息
概述货号 | 16776-10mg |
描述 | Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.1 Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid, fluprostenol.25-trans Fluprostenol is an impurity that is routinely found in bulk preparations of fluprostenol in amounts ranging from 1-3%. This impurity occurs in the finished prodrug Travoprost in similar amounts. The pharmacology of 5-trans fluprostenol has not been studied extensively to date. |
别名 | 5,6-transFluprostenol; |
性能供应商 | Cayman |
应用文献 |
1.Hellberg, M.R.,Sallee, V.L.,McLaughlin, M.A., et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. Journal of Ocular Pharmacology and Therapeutics 17(5), 421-432 (2001). 2.Sorbera, L.A., and Castañer, J. Travoprost. Drugs of the Future 25, 41-45 (2000).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 458.5 |
分子式 | C23H29F3O6 |
CAS号 | 57968-83-9 |
稳定性 | ≥ 2 years |
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