| 货号 | 10010742-10mg |
| 描述 | Prostaglandin F2α(PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.1,2,3 Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable analogs of PGF2α and potent agonists for the FP receptor.4 17-phenoxy trinor PGF2α ethyl amide is a lipophilic analog of 17-phenoxy trinor PGF2α (Item No. 10010839). Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
| 别名 | 17-phenoxy trinor PGF2α ethyl amide; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Samuelsson, B.,Goldyne, M.,Granström, E., et al. Prostaglandins and thromboxanes. Annual Reviews of Biochemistry 47, 997-1029 (1978). 2.Speroff, L. and Ramwell, P.W. Prostaglandins in reproductive physiology. American Journal of Obstetics and Gynecology 107, 1111-1130 (1970). 3.Crankshaw, D.J. and Gaspar, V. Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes. Journal of Reproduction and Fertility 103, 55-61 (1995). 4.Balapure, A.K.,Rexroad, C.E., Jr.,Kawada, K., et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor. Biochemical Pharmacology 38, 2375-2381 (1989). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 431.6 |
| 分子式 | C25H37NO5 |
| CAS号 | 1421369-12-1 |
| 稳定性 | ≥ 1 year |
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