| 货号 | 0342/50 |
| 别名 | (RS)-3,5-Dihydroxyphenylglycine |
| 供应商 | Tocris |
| 生物活性 | Selective group I metabotropic glutamate receptor agonist which activates both mGlu1 and mGlu5. Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D. (S)-3,5-DHPG (Cat. No. 0805) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 183.16 |
| 分子式 | C8H9NO4 |
| 可溶性/溶解性 | Soluble to 10 mM in water |
| CAS号 | 19641-83-9 |
| 参考文献 | Mistryet al (1998) Regulation of phosphoinositide turnover in neonatal rat cerebral cortex by group I- and II-selective metabotropic glutamate receptor agonists. Br.J.Pharmacol. 123 581. PMID: 9504400. Palmeret al (1997) The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus. Neuropharmacology 36 1517. PMID: 9517422. Pellegrini-Giampietroet al (1996) Pharmacological characterization of metabotropic glutamate recpetors coupled to phopholipase D in the rat hippocampus. Br.J.Pharmacol. 118 1035. PMID: 8799579. Itoet al (1992) 3,5-Dihydroxyphenylglycine: a potent agonist of metabotropic glutamate receptors. NeuroReport 3 1013. PMID: 1362358. |