| 货号 | 5961/50 |
| 别名 | N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl |
| 供应商 | Tocris |
| 生物活性 | Selective TrkB receptor agonist. Protects neurons from excitotoxicity. Protects retinas from light-induced retinal degeneration (LIRD) in vivo. Blood brain barrier and blood-retinal barrier penetrant. |
| 运输条件 | Ambient |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 301.34 |
| 分子式 | C16H19N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Setterholmet al (2015) Gram-scale, chemoselective synthesis of N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-oxopiperidine-3-carboxamide (HIOC) Tetrahedron Lett. 56 3413. PMID: 26028783. Shenet al(2012)N-acetyl serotonin derivatives as potent neuroprotectants for retinas Proc.Natl.Acad.Sci.USA 109 3540. PMID: 22331903. |