G10 ( )
货号：
5944/50 基本售价：
7812.6 元 规格：
50 mg
产品信息
概述| 货号 | 5944/50 |
| 别名 | 4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Activator of STING-dependent signaling; exhibits no direct binding affinity for STING. Stimulates IRF-3-induced transcription and induces IFNα and IFNγ gene expression in human fibroblasts. Exhibits no effect on NF-κB signaling. Blocks viral replication in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 430.88 |
| 分子式 | C21H16ClFN2O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Saliet al (2015) Characterization of a novel human-specific STING agonist that elicits antiviral activity against emerging alphaviruses. PLoS Pathog. 11 e1005324. PMID: 26646986. |
