| 货号 | 0352/50 |
| 供应商 | Tocris |
| 生物活性 | Structural analog of acetylcholine that acts as a nicotinic agonist (Ki = 29.9 nM at α4β2). Upregulates the number of α4β2 binding sites in M10 cells in vitro by 440%. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 284.14 |
| 分子式 | C8N17IN2O |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 75667-84-4 |
| 参考文献 | Warpmanet al (1998) Regulation of nicotinic receptor subtypes following chronic nicotinic agonist exposure in M10 and SH-SY5Y neuroblastoma cells. J.Neurochem. 70 2028. PMID: 9572289. Spivaket al (1988) Binding of semirigid nicotinic agonists to nicotinic and muscarinic receptors. Mol.Pharmacol. 36 177. PMID: 2747625. Spivaket al (1986) Structural and electronic requirements for potent agonists at a nicotinic receptor. Eur.J.Pharmacol. 120 127. PMID: 3485051. |