货号 | 0867/250 |
别名 | 1-(4-Methoxybenzoyl)-2-pyrrolidinon |
供应商 | Tocris |
生物活性 | Nootropic, with modulatory actions through allosteric potentiation of AMPA specific receptors, reduction of glutamate receptor desensitization and potentiation of metabotropic glutamate receptor activity. Anxiolytic following systemic administration. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 219.24 |
分子式 | C12H13NO3 |
可溶性/溶解性 | Soluble to 25 mM in ethanol and to 100 mM in DMSO |
CAS号 | 72432-10-1 |
参考文献 | Nakamura and Kurasawa (2001) Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur.J.Pharmacol. 420 33. PMID: 11412837. Isaacson and Nicholl (1991) Aniracetam reduces glutamate receptor desensitisation and slows the decay of fast excitatory synaptic currents in the hippocampus. Proc.Natl.Acad.Sci.U.S.A. 88 10936. PMID: 1660156. Itoet al (1990) Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. J.Physiol. 424 553. PMID: 1975272. |