| 货号 | 18003-50mg |
| 描述 | Ghrelin is an endogenous ligand for the growth hormone (GH) secretagogue receptor (GHSR).1 Ibutamoren is an orally-active, non-peptidic agonist of GHSR (Kd = 0.4 nM) and, as a result, is a GH secretagogue.2,3 It elevates GH in dogs after oral doses as low as 0.125 mg/kg, without significantly changing plasma levels of aldosterone, luteinizing hormone, thyroxine, or prolactin.4 |
| 别名 | L-163,191;MK-0677; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kojima, M.,Hosoda, H.,Date, Y., et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660 (1999). 2.Howard, A.D.,Feighner, S.D.,Cully, D.F., et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 273, 974-977 (1996). 3.Smith, R.G.,Pong, S.S.,Hickey, G., et al. Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland. Recent Progress in Hormone Research 51, 261-286 (1996). 4.Patchett, A.A.,Nargund, R.P.,Tata, J.R., et al. Design and biological activities of L-163,191 (MK-0677): A potent, orally active growth hormone secretagogue. Proceedings of the National Academy of Sciences of the United States of America 92(15), 7001-7005 (1995). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 624.8 |
| 分子式 | C27H36N4O5S • CH3SO3H |
| CAS号 | 159752-10-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |